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KMID : 0605620180250030079
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Journal of Korean Society of Biological Psychiatry
2018 Volume.25 No. 3 p.79 ~ p.87
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Effect of Stress and Serotonin-Transporter-Linked Polymorphic Region Variants on Internet Gaming Disorder in Korean Adults
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Hong Hyung-Sook
Jeong Jo-Eun
Cho Hyun
Kwak Su-Min
Choi Mi-Ran
Choi Jung-Seok
Choi Sam-Wook
Kim Dai-Jin
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Abstract
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Objectives : Internet gaming disorder (IGD) is known to be related to stress and the serotonin-transporter-linked polymorphic region (5-HTTLPR) that is known to be associated with stress and has been studied to affect various psychiatric illness outbreaks. We tried to examine the relationship between stress, 5-HTTLPR and IGD.
Methods : A total of 59 participants with IGD, diagnosed according to the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria and 67 normal controls (NC) were enrolled. The IGD group and the NC were compared using chi-square test and independent sample t-test, and logistic regression analysis was used to examine the relationship between stress, the 5-HTTLPR, and IGD.
Results : The mean scores for anxiety, impulsivity and stress were significantly higher in the IGD group than in the NC. In addition, there was a significant association between stress and IGD [odds ratio (OR) = 1.172, 95% confidence interval (CI) = 1.008-1.362].
Conclusions : This study showed that stress would affect IGD. Therefore, the evaluation and management of stress should be included in the diagnosis and treatment of IGD.
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KEYWORD
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Internet gaming disorder, Stress, Serotonin-transporter-linked polymorphic region
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